1. By submitting a manuscript, the authors affirm that the manuscript has not been published previously and is not currently under consideration for publication elsewhere. The authors also affirm that the manuscript does not contain the content of the results of others. Copyright of the manuscript including CD-ROM, Internet and other media is assigned to the editorial office of JoS from the date on which the manuscript is accepted for publication.

2.Manuscript must be written in English, and should be neatly typed, double spaced, with A4 paper size.

3.Manuscript should have a clear point of view and reliable data, and should be concise and focused. If the manuscript contains similar or closely relevant contents to the published papers, the authors should show them in references.

1)Title, Author, Institution, and Abstract

 * Title: The title should be concise, precise but informative, and should not be over 10 substantive words.  * Author: The names of authors should be confirmed before submitting a manuscript and cannot be changed after submission.  * Institution: The full name of the institution, the city where it is located, and the postal code are needed.

* Abstract: The purpose, method, results, and conclusion of the research work should be briefly presented in third person. The abstract should not normally exceed 200 words. As the abstract is not part of the text, it should be complete in itself; no table numbers, figure numbers, references or displayed mathematical expressions should be included.

2).Key words and PACS or EEACC numbers

* Key words: Between 3 and 6 key words should be provided. * PACS or EEACC numbers: Between 1 and 3 numbers should be given.

3). Foundation and Contract number:The supporting organization and contract number should be given.

4). Abbreviations, Acronyms, and Units of measure

* Abbreviations and Acronyms: All acronyms and abbreviations should be clearly explained when they first appear in the abstract or text. * Units of Measure: The SI system should be used, and all units used should be consistent throughout the manuscript.

5). Figures and Tables

* Figures (Including photographs): Figures should be arranged sequentially with Arabic numerals, and should be clear, easy to read and of the best possible quality. The width of the figures should be not over 8 cm, and the lines must be smooth, clean and uniform. The tick marks on figure axes should point inward. Characters should appear as they would be set in the main body of the manuscript. Photographs should be in good contrast with details clearly distinguishable. We will normally use figures as submitted; it is therefore your responsibility to ensure that they are legible and technically correct. The use of colour in figures is freely available in the online version of the manuscript, but authors will be charged RMB 1 200 per colour journal page in the printed version.

* Tables: Tables should be numbered serially and referred to in the text by number (Table 1, etc). Concise and precise three-line tables should be used.

6). References

References should be numbered consecutively, in the order in which they appear in the text, with square brackets enclosing the number. The information about the references cited should be provided in its entirety. References should not contain un-published data.

Normally, at least 15 references should be provided, among which at least 10 references should be published in the past 5 years.